Evaluation of activities of Mitragyna parvifolia fruit extract

Ethanolic extract of the Mitragyna parvifolia was evaluated for antiinflammatory, analgesic and antimicrobial activities. The extract showed very significant analgesic and anti-inflammatory potential. The analgesic activity was significant at the dose of 500 mg/kg (P< 0.01) while the doses of 250 and 100 mg/kg showed only promising results. The extract at the dose of 500 mg/Kg showed very high % inhibition in edema volume comparable to standard drug Diclofenac sodium (50 mg/Kg, i.p.). The plant extract did not exhibit any anti-bacterial potential against Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa.